Blog Entries from April 2014

Central Nervous System Involvement with Diabetic Peripheral Neuropathy

Monday, April 21st, 2014

Diabetic Peripheral Neuropathy (DPN) causes chronic pain (painful diabetic neuropathy) and sensory loss that increases the risk of foot ulcers.  DPN has traditionally been viewed as a disease of the peripheral nerves.  However, several recent studies hinted at additional involvement of the central nervous system (CNS).  Now a novel study using Magnetic Resonance Imaging (MRI) by Dinesh Selvarajah and colleagues published in Diabetes Care (http://www.ncbi.nlm.nih.gov/pubmed/24658391) demonstrates that patients with DPN have structural changes in the brain.  Specifically, the study found peripheral gray matter volume loss in regions of the brain associated with sensory and pain perception.  These findings may have far reaching implications for treating DPN.  If DPN leads to changes in the CNS, then early detection and prevention are critical to mitigate the risk of permanent and severe symptoms.  On the other hand, the brain has an amazing capacity to compensate for the focal loss of neurons (i.e., gray matter), which is called plasticity.  Pharmacological and neurophysiological techniques that enhance plasticity, which include transcutaneous electrical nerve stimulation, may therefore represent novel therapeutic approaches. Read More

Posted by NeuroMetrix in Painful Diabetic Neuropathy

Extending the Life of Your Electrode

Saturday, April 5th, 2014

Each SENSUS electrode should last two weeks before you need to use a new one.  But if you’re finding that they’re wearing out more quickly, here are a few simple things you can do to make sure you get the full life out of your electrodes:

  1. Cover the electrode with the liner when not in use.  This will help protect the gel from drying out and picking up dust and dirt, which can eventually interfere with the delivery of therapeutic stimulation by the device.
  2. Hydrate your electrode.  The gel on the electrodes is a hydrogel, which means that it will absorb and retain water.  The gel will naturally start to dry when exposed to air and used on skin (in drier months, your skin will absorb moisture from the electrode).  If you notice that the gel is no longer tacky enough to stick to your skin, remove it from the device and run it under water for 10-20 seconds and let air dry.
  3. Hydrate your skin.  For some individuals, the gel of the electrode adheres particularly well to their skin (and may even begin to separate from the electrode).  If you find that this happens to you, applying a light moisturizer 30 minutes prior to using SENSUS may help prevent this from occurring; be sure to let the moisturizer absorb fully into the skin.
  4. Storage: When not in use, store at room temperature in a location away from direct sunlight.
Read More

Posted by NeuroMetrix in SENSUS Operation